Keno is a simple casino game and as such there is really no strategy. Lady luck may or may not be on your side. What you can do is shop around at various casinos to find the best pay tables.
The pay tables are based upon the odds of catching 0-20 hits. If you catch all 20 spots then consider yourself a world record holder because the odds of getting all 20 picks correct are astronomical. The odds are best at 4, 5 and 6 catches but these will probably not get you paid. Instead hope to get 0,1,2,3 or 7 through 20 catches which will get you paid. Here is the complete list of odds:
0 catches – 1 in 843.380
1 catch – 1 in 86.446
2 catches – 1 in 20.115
3 catches – 1 in 8.009
4 catches – 1 in 4.877
5 catches – 1 in 4.287
6 catches – 1 in 5.258
7 catches – 1 in 8.826
8 catches – 1 in 20.055
9 catches – 1 in 61.420
10 catches – 1 in 253.801
11 catches – 1 in 1,423.822
12 catches – 1 in 10,968.701
13 catches – 1 in 118,084.920
14 catches – 1 in 1,821,881.628
15 catches – 1 in 41,751,453.986
16 catches – 1 in 1,496,372,110.872
17 catches – 1 in 90,624,035,964.712
18 catches – 1 in 10,512,388,171,906.553
19 catches – 1 in 2,946,096,785,176,811.500
20 catches – 1 in 3,535,316,142,212,173,800.000
Enjoy your Keno!